S1. Omics Data Analysis in Safety Assessment

Application of Omics Data Analysis in Safety Assessment

Session 1 Chair: Richard Paules

OpenTox USA 2017 Session 1 Chair: Richard Paules
PRESENTING AUTHOR: 
Richard S. Paules 
CHAIR PROFILE: 

Richard S. Paules, Ph.D., is the Acting Chief of the Biomolecular Screening Branch (BSB) in the Division of the National Toxicology Program at the National Institute of Environmental Health Sciences, NIH...

SESSION DESCRIPTION: 

Members of the public, knowingly or unwittingly, are exposed to thousands of chemicals and environmental agents that have potential to adversely affect their health when exposed at sufficiently high levels and/or for prolonged duration...

S1: The Resolution of Concentration Response: High Throughput Transcriptomics (S1500+) Paired with In Vitro Liver Models Reveal the...

S1: The Resolution of Concentration Response:  High Throughput Transcriptomics, OpenTox USA 2017
PRESENTING AUTHOR: 
Stephen S. Ferguson 
ABSTRACT CONTENT / DETAILS: 

As part of Phase III of the Tox21 Program, we are developing improved approaches to investigate chemical safety/toxicity potential in humans. Initial efforts have focused on developing and integrating organotypic in vitro liver screening models (2D & 3D)...

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