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Lucian Farcal 
Scientific Project Manager at Edelweiss Connect

Dr Lucian Farcal studied veterinary medicine at the University of Agricultural Sciences and Veterinary Medicine in Cluj-Napoca (Romania) and he received the PhD degree at the same University in 2009.

After the doctoral studies he has worked as scientific officer at the European Commission’s Joint Research Centre in the area of alternative methods to animal testing with a focus on the respiratory system, followed by a postdoc and project management position at Karolinska Institutet in the area of nanosafety research. His scientific interest is focused on development and optimisation of alternative methods (in vitro and in silico) and integration of 3Rs principles into testing strategies, as well as using the knowledge management process as a support tool to these areas.

At EwC, he has led the project management of the eNanoMapper project through its successful review and completion and has assumed this role in several other projects (e.g. OpenRiskNet). He is currently involved in different EU or commercial projects, with a role in the scientific and project management implementation, knowledge transfer, design and development of different EwC applications and reporting. These include also activities in the area of nanomaterials research and nanosafety, where EwC is developing a set of applications to support the collection and sharing of methods and data.

Dr. Farcal is contributing to the EwC laboratory establishment at Technological Park in Basel and implementation of its working program, involving research and training activities. He is leading the activities at EwC in the area of 3Rs knowledge management by initiating and developing different applications and projects. Dr. Farcal is the author and co-author of >10 peer-reviewed articles and several other scientific contributions.

OpenTox Euro 2019: ACEnano knowledge infrastructure to support data collection, methods optimisation and knowledge sharing in the area of physicochemical characterisation of nanomaterials

ACEnano knowledge infrastructure (KI) supports the activities related to data collection and method optimisation in the area of physicochemical characterisation of nanomaterials. The KI provides a central place to access harmonised and standardised methods and data, supporting the implementation of Findable, Accessible, Interoperable and Reusable (FAIR) data principles, the reproducibility and documentation process towards the goal of generating reference resources for nanomaterials risk assessment.

The KI includes instances to accommodate data and protocols. The protocols database facilitates adding, sharing and comparing methods in a questionnaire-like format guiding users through the documentation process from starting material identification to sample preparation, measurement and data processing. The data warehouse offers long-term storage of the results in a reusable format that are directly linked to the methods applied.

A public version of the data warehouse is being integrated in the NanoCommons ecosystem. By semantic annotation and linking, this guarantees harmonisation and interoperability with other data sources of the EU NanoSafety Cluster like the eNanoMapper and NanoFASE.

The development of the KI is supported by ACEnano (EU Horizon 2020 NMBP project no. 720952), while its availability to a wider community is assured by the activities in NanoCommons (Horizon 2020 INFRAIA project no. 731032).