OpenTox Molecules with Androgenic Activity Resource (MAAR)
The increasing prevalence of endocrine-disrupting chemicals (EDCs) and their potential adverse effects on human health underscore the necessity for robust tools to assess and manage associated risks. To facilitate the utilization of androgenic activity data in chemical risk assessment, we developed the Molecules with Androgenic Activity Resource (MAAR), a pioneering open-access platform designed to streamline and enhance the risk assessment of chemicals with androgenic activity. The development of MAAR involved the integration of diverse data sources, including data from public databases and mining literature, to establish a reliable and versatile repository. The platform employs a user-friendly interface, enabling efficient navigation and extraction of pertinent information. MAAR is poised to advance chemical risk assessment by offering unprecedented access to information crucial for evaluating the androgenic potential of a wide array of chemicals. The open-access nature of MAAR promotes transparency and collaboration, fostering a collective effort to address the challenges posed by androgenic EDCs.
The Androgenic Activity Database (AADB)
Observable Notebook
The Observable notebook (https://observablehq.com/@saferworldbydesign/aadb-notebook) for the MAAR database is available through a URL and can be easily shared with anyone. The notebook addresses a simple use case where a user wants to search the database for a particular compound.