Thomas Luechtefeld is an entrepreneur and AI researcher dedicated to building tools that improve public health and safety. As the founder of Insilica.co, he has developed platforms like Sysrev, an AI assisted document review tool, and Biobricks.ai, a data registry for open chemical and biological data. Thomas specializes in applying artificial intelligence to challenges in toxicology, chemical safety, and environmental health. He has collaborated with academic and industry partners on projects that advance open science and improve data accessibility. With a focus on practical solutions, his work supports better decision-making and fosters collaboration across disciplines.
OpenTox Summer School 2025
A Data Onramp for Toxicology
This presentation introduces innovative solutions for toxicology data management and analysis. We explore BioBricks.ai, a package manager for toxicology data, and Chemharmony, a comprehensive chemical data integration platform. These tools address challenges such as data silos and heterogeneous schemas, enabling efficient data harmonization and integration across multiple sources. We discuss Toxindex.com, a platform integrating computational services for chemical hazard assessment, and introduce Property Sequence Transformers for molecular language modeling. The presentation also covers the development of a semantic knowledge graph for toxicology, aimed at improving data discoverability and accessibility for AI-driven applications. Real-world applications, including safer polymer development and literature-based discovery, demonstrate the practical value of these approaches. Attendees will gain insights into cutting-edge data integration techniques and their potential to accelerate toxicology research and decision-making processes, ultimately improving chemical safety assessment and regulatory compliance.