Tamara Krsmanovic is a head of business development at EvalyteBio. She has 10+ years of industry experience, combining scientific expertise with commercial strategy across target safety reviews, scientific data curation, marketing, market analysis, and competitive intelligence. She obtained her PhD at the Institute of Microbiology in Düsseldorf, Germany studying protein transport in yeast. As a Post-Doc in Manchester, UK, at Paterson Institute for Cancer Research and at the LIMES Institute in Bonn, she studied biochemistry of proteins involved in cell division in yeast and in endocytosis in human cell culture and fruit fly.
OpenTox Virtual Conference 2026
The Target Safety Review (TSR) is a foundational document that initiates target safety assessment - a systematic process for identifying, characterizing, and managing safety risks associated with drug targets. By organizing existing knowledge on a target's characteristics, biology, and disease relevance, the TSR reveals potential risks and supports mitigation strategies such as candidate refinement and project strategy adjustments. At EvalyteBio, we specialize in de-risking therapeutic targets and delivering high-impact scientific communication, drawing on industry best practices and real-world drug discovery experience. In this presentation, we will show how integrating biological, mechanistic, and safety information produces a truly robust target safety assessment. We will also examine how far AI has come in compiling TSRs, exploring its real capabilities and current limitations.