Thomas Luechtefeld is an entrepreneur and AI researcher dedicated to building tools that improve public health and safety. As the founder of Insilica.co, he has developed platforms like Sysrev, an AI assisted document review tool, and Biobricks.ai, a data registry for open chemical and biological data. Thomas specializes in applying artificial intelligence to challenges in toxicology, chemical safety, and environmental health. He has collaborated with academic and industry partners on projects that advance open science and improve data accessibility. With a focus on practical solutions, his work supports better decision-making and fosters collaboration across disciplines
A Data Onramp for Toxicology
The field of toxicology faces significant challenges with data silos, inconsistent schemas, and limited integration of diverse datasets. To address these issues, platforms like BioBricks.ai, Toxindex.com, and Sysrev.com provide innovative solutions for harmonizing and leveraging toxicological data. BioBricks.ai serves as a data package manager, enabling streamlined discovery, versioning, and integration of datasets. Chemharmony, a key component, consolidates information from over 15 chemical property sources, supporting analyses across millions of chemical activities. Toxindex.com offers predictive tools for assessing chemical hazards, with features like ToxWatch for monitoring database updates and ToxScore for model-driven hazard predictions. Sysrev.com enhances the integration of unstructured data, such as PDFs and scientific publications, with AI-powered curation and analysis tools. Together, these tools provide a scalable onramp for toxicology data, accelerating workflows and enabling the application of AI-driven insights to enhance safety assessments, regulatory compliance, and research innovation. Through case studies and demonstrations, this session highlights their transformative impact on data accessibility and usability in toxicology.
